Antioxidant enzymes come to the rescue of DNA damage

The nucleus has historically been considered metabolically inert, importing all of its needs through supply chains in the cytoplasm. Now, a new study led by researchers at the Center for Genomic Regulation (CRG) in Barcelona and CeMM/Medical University of Vienna has revealed that in a state of crisis, such as DNA damage, the nucleus protects itself by calling on antioxidant enzymes to save. The new results are published in Biology of molecular systems in an article titled A metabolic map of DNA damage response identifies PRDX1 in the control of…

Read More